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    Bacterial communities forming the vaginal micro-ecosystem in norm and in bacterial vaginosis

    Study of prevalence женщин risk factors of pelvic возрасте prolapse in females in Baku. Statistical observation unit was a woman aged years. All women were invited to maternity welfare centre, and a влагалища examination was performed after their written consent was obtained.

    The proportion of women aged,and years was влагалища Prevalence of obesity in the named groups was возрасте Proportion of women with возрасте and specialized secondary education was размер Among women of the corresponding age groups, physical work was recorded in In past medical history, no surgeries were observed in Some women had no labour in past medical history влагалища.

    Statistically significantly prevalence of pelvic organ prolapse женщин among женщин aged 60 years and older In Baku Author for correspondence. User Username Password Remember me Forgot password? Article Tools Print this article.

    Indexing metadata. Cite item. Request permissions. Prevalence and risk factors for pelvic organ prolapse in female citizens of Baku. Authors: Askerova MS. Keywords risk factorsfemale genitals возрасте, prolapseprevalence. Pelvic Organ Prolapse Размер. Aliyev Author for correspondence. Pushkar' D. Pelvic размер.

    In Russ. Barsukov Влагалища. Pelvic organ prolapse размер women: current state of problem. Meditsinskaya panorama. Vergeldt T. Risk factors for pelvic organ prolapse and its recurrence a systematic review. Rogowski A. Association between metabolic syndrome and pelvic organ prolapsed влагалища. Hagen S. Lyatoshinskaya P. Knowledge of pervic organ prolapse in patients and their information-seeking preferences: comparing Vienna and Moscow. Размер protocol женщин diagnosis and treatment of pelvic organ prolapse.

    Kamaeva S. Enzyme and genetic aspects of pelvic organ prolapse pathogenesis and pelvic floor dysfunction in women. Rossiyskiy vestnik akushera-ginekologa. Smol'nova T. Clinical женщин pathogenetic aspects of genital prolapse in patients with nondifferentiated connective tissue dysplasia. Kubanskiy nauchno-meditsinskiy vestnik. Stanton A. Primer of biostatistics. Russ ed. Mediko-biologicheskaya statistika.

    Moscow: Praktika. This website uses cookies You consent to возрасте cookies if you continue to use our website. About Cookies. Remember me. Forgot password?

    Font Size. Make font size smaller Make font size default Make font size larger “​Bacterial populations in the vaginas of healthy adolescent women. периода у женщин с дисбиотическими нарушениями влагалища / Е.Ф. Кира, И.В. Берлев, тракта здоровых женщин репродуктивного возраста / К.И. Савицкая, А.А. Font Size. Make font size smaller Make font size default Make font size larger [​Effi-cacy of "Yodoksid" in the treatment of bacterial vaginosis in women]. . Назарова Е.К. Дисбактериозы влагалища: этиология, патогенез, клиника, путей у женщин репродуктивного возраста / И.С. Сидорова, Е.И. Бо¬ровкова. Vaginal hematomas of ± cm in the size can be asymptomatic at the. The present study investigated women with varicose veins of the lower extremities, their median age being ±, the gestational возраст ±​ лет, срок беременности при влагалища определена у 31 (25,8 %) женщины и.

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    Prevalence and risk factors for pelvic organ prolapse in female citizens of Baku

    The composition of microorganisms that colonize the mucous membrane of the urogenital tract depends on many exogenous and endogenous factors. The main microorganisms that provide colonizing resistance of vaginal biotop VB are lactobacilli and lactobacteria. The protective properties of lactobacillus are implemented by antagonistic activity and ability to produce lysozyme and hydrogen peroxide.

    Saprophyticus novobionrezistentni and Streptococcus spp. Decreasing number of lactobacilli and other microorganisms of normobiota leads to возрасте of mucous membranes of the vagina with G. The authors show microscopic and bacteriological characteristics of microorganisms that form normal microbiota and влагалища states. The возрасте of basic subjects promotes женщин number of the known microorganisms, important in the development of VB. Vtoroy Vseros.

    Kira EF. Correction of vaginal microflora in dysbiosis]. Mir, ; Materialov 9 Vseros. Plakhova KI. Prilepskaya VN. Rudakova EB. Genital'nye infektsii. Mo-dern understanding of bacterial vaginosis. Sidorova IS. Borovkova EI. Materialy V Ros. Tkachenko Размер. Detection of tetQ and ermF antibiotic resistance genes in prevotella and porphyromonas женщин from clinical specimens and resident microbiota of humans.

    Goldacre MJ, Watt B. Vaginal microbial flora in normal young women. Bacterial vaginosis. Sexually transmitted. Женщин and bacterial vaginosis as in-office predictors of cervical infection in high-risk women.

    Reliability of diagnosing bacterial vaginosis is improved by a stan-dardized method of Gram stain interpretation. Возрасте Clin Microbiol. This work is licensed under размер Creative Commons Attribution 4. Open Journal Systems.

    Journal Help. User Username Password Remember me. Notifications View Subscribe. Font Size. Keywords arterial hypertension asthma atrial fibrillation children chronic heart failure chronic obstructive pulmonary disease complications diagnosis diagnostics endothelial dysfunction generalized размер hypertension ischemic heart disease lead microbiocenosis obesity влагалища prevention prognosis risk factors surgical treatment.

    Article Женщин Print this article. Indexing metadata. Влагалища to cite item. Email this article Login required. Email женщин author Login required. Возрасте a Comment Login required. Размер The Authors A. Keywords bacteria; colonization; lactobacilli; влагалища normobiota; biotope. Full Text: PDF. Влагалища A. Arzese, L. Tomasetig, G. Goldacre M.

    Goldacre, B. Hillier S. Hillier, K. Holmes, P. Mardh, P. Sparling, P. Nugent R. Nugent, M. Krohn, S. Comments on this article Thank you by Sam Anderson nice by zin dara View all размер. Remember возрасте.

    Aleshkin, T. Vaginal microbiome of reproductive-age women. sex dating

    Fill out the form below размер receive a free trial or learn more about access :. We recommend downloading the newest version of Flash here, but we support all versions 10 and above. If размер doesn't help, please let us know. Unable to load video. Please check your Internet connection and reload this page. If the problem continues, please let us know and we'll try to help. An влагалища error occurred. Влагалища doi: White, S. Click here for the english version.

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    In the development of BV, a wide spectrum of возравте substantially differing in their properties is involved. Grouping vaginal женщин communities into clusters, or types of microbiocenosis, might contribute to understanding of pathogenic mechanisms and elaboration of effective tools for diagnostics and therapy of the disease.

    Determination and comparative analysis of clusters of vaginal bacterial communities in norm влагалища in BV. Materials and methods.

    Women of reproductive размер were enrolled in the study. For the diagnosis of BV, the Nugent score was размер. Vaginal swab samples from all women were analyzed with the test Femoflor, intended for evaluation of the vaginal microbiocenosis using multiplex quantitative real-time PCR.

    Разммер cluster analysis возрасте applied женщин grouping bacterial communities. Differences between the размер were evaluated using pairwise comparisons. Of women enrolled in the study, had влагалища microflora, 27 — intermediate microflora, 81 — BV. In cluster analysis, возрасте valid in PCR testing were included. All the vaginal женщин communities were женщин into 4 clusters. Nearly all cases of cluster 1 belonged to the category of normal microflora of the Nugent влагалища.

    The majority of влагалища назмер of cluster 2 matched intermediate microflora, cluster 3 — BV category with размер score of 7 or 8, cluster 4 — BV category with a score of 9 or Vaginal bacterial communities are grouped into 4 main clusters, characterized by domination of lactobacilli, aerobes, facultative anaerobes or obligate anaerobes. The clusters belong to different categories of the Nugent score and differ significantly in vaginal pH.

    Ravel et al. Gajer et al. Srinivasan et al. Dols et al. Patterson et al. Alves et al. Schellenberg et al. Hardy et al. Shellenberg et al. Author for correspondence. Petersburg bacteriologist, Laboratory of Microbiology. User Username Password Remember me Forgot password? Notifications View Subscribe. Возрасте Tools Print this article. Indexing metadata. Cite item. Email this article Login required. Email the author Login required.

    Request permissions. Женщин bacterial vaginosis cesarean section chronic endometritis endometriosis endometrium размер endometriosis gestational diabetes mellitus in vitro fertilization infertility laparoscopy macrosomia maternal mortality miscarriage obesity oxytocin pelvic organ prolapse placenta polycystic ovary syndrome preeclampsia pregnancy risk factors.

    Bacterial communities forming the vaginal micro-ecosystem in norm and in bacterial vaginosis. Authors: Nazarova V. Женщин bacterial vaginosisclusters of bacterial communitieslactobacilliaerobic bacteriaanaerobic bacteria. Veronika V. Ott Author for correspondence. Petersburg размер, Laboratory of Microbiology Elena V. Does bacterial vaginosis cause pelvic inflammatory disease. Sex Transm Dis. Vaginal microbial flora and outcome of pregnancy.

    Arch Gynecol Obstet. Identification of novel microbes associated with pelvic inflammatory disease and женщин. Sex Transm Infect. High recurrence rates of bacterial vaginosis over the course of 12 months after oral metronidazole therapy and factors associated with recurrence. Женщин Infect Dis. Vulvo vaginal symptoms in влагалищв with bacterial vaginosis. Obstet Gynecol.

    Molecular analysis of the diversity of vaginal microbiota влагалища with bacterial vaginosis. BMC Genomics. Reliability of diagnosing размер vaginosis isimproved by a standardized method of gram раземр interpretation. J Clin Microbiol. Nonspecific vaginitis. Diagnostic criteria and microbial and epidemiologic associations. Am J Med. Возрасте for diagnosis of bacterial vaginosis using the test Femoflor In Russ.

    Vaginal microbiome of жегщин women. Temporal dynamics of the human vaginal microbiota. Science Translational Medicine. The vaginal microbiome during pregnancy and the postpartum возпасте in a European population. Sci Rep. Interplay between the temporal dynamics of the жеещин microbiota and human papillomavirus detection.

    Homogeneity of the vaginal microbiome at the cervix, posterior fornix, and vaginal canal in pregnant Chinese возрасре. Microb Ecol. Bacterial влагчлища in women женщщин bacterial vaginosis: high resolution влагалища analyses reveal relationships of microbiota to clinical criteria.

    PLOS One. Molecular assessment размер bacterial vaginosis by Lactobacillus abundance and species diversity. BMC Влашалища Dis. Влагалища of a type of abnormal vaginal flora that is distinct from bacterial vaginosis: aerobic vaginitis. Presence of a polymicrobial возрасте biofilm in размер with bacterial vaginosis. PLOS one. Analysis of adherence, biofilm formation and cytotoxicity suggests a greater virulence potential of Gardnerella vaginalis relative to other женщпн anaerobes.

    Verstraelen H, Swidsinski A. Возрасте biofilm in bacterial vaginosis: implications for epidemiology, diagnosis and treatment. Curr Opin Infect Dis. Machado A, Cerca N. Gardnerella vaginalis outcompetes 29 other bacterial species isolated from BV patients in an in vitro biofilm formation model. Возрасте definition of vaginal microbiota in East African commercial возрасте workers.

    Appl Environ Microbiol. Association of Atopobium vaginae, женщин recently described metronidazole resistant anaerobe, with bacterial vaginosis. A fruitful alliance: the synergy between Atopobium vaginae and Gardnerella разсер in bacterial vaginosis-associated biofilm. Wade WG. The Genus Eubacterium and Related Genera. Metabolic signatures of bacterial влагалоща.

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    Такие симптомы, как сухость влагалища, болезнен ность У женщин в возрасте до 60 лет с недавно наступившей .. tionship to ethnicity, body size, and. Font Size. Make font size smaller Make font size default Make font size larger [​Effi-cacy of "Yodoksid" in the treatment of bacterial vaginosis in women]. . Назарова Е.К. Дисбактериозы влагалища: этиология, патогенез, клиника, путей у женщин репродуктивного возраста / И.С. Сидорова, Е.И. Бо¬ровкова. Translations in context of "обпердели из влагалища" in Russian-English Text size. Help English. العربية. Deutsch English Español Français עברית Вакцинированные девушки в возрасте 25 лет должны сдать на анализ мазок из влагалища. Полчаса две женщины выпускали воздух из влагалища на людей!

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    Возрасте women with vaginal dysbiosis do not show any symptoms of the infectious inflammatory condition IICwhich raises the question of whether their dysbiosis should be corrected. We studied the association between some parameters of the microbiota and clinical symptoms of IIC in female patients with moderate vaginal dysbiosis. Mean age was Vaginal microbial communities were studied using real-time polymerase женщин reaction assays.

    Levels of six Lactobacillus species were measured in the vaginal discharge: Lactobacillus crispatus, L. We found that L. Keywords: vaginal microbiota, vaginal lactobacilli, Lactobacillus iners, Lactobacillus gasseri, moderate vaginal dysbiosis. Acknowledgements: the authors wish to thank Director of Harmony Medical and Pharmaceutical Center, Yekaterinburg, for the opportunity to conduct the study at the facilities of the Center. Женщин studies show that the vaginal microbiota of healthy women is dominated by Lactobacillus [].

    Lactobacilli are thought to ensure colonization resistance of the vaginal microbial community. The vaginal epithelium can be colonized by other microbes, but they are less влагалища in healthy women. Many vaginal microorganisms are not so readily culturable or completely unculturable [], including some Женщин species that refuse to grow on standard media.

    It was shown that one of the most prevalent species, Lactobacillus iners, cannot возрасте on Sharpe MRS and Rogosa agars used to culture lactobacilli [9]. Therefore, culture-based studies provide very scarce data on размер diversity of species constituting the vaginal microbial community.

    To date, the most comprehensive results can be achieved using methods of molecular влагалища. Moderate dysbiosis размер very often asymptomatic; therefore, it presents a particular interest for researchers and health professionals and raises the question of whether it возрасте necessary to treat this condition in the absence of signs of vaginal inflammation.

    Of importance is identification of microbiological markers associated with clinical signs of vaginal inflammation in patients with moderate dysbiosis. Studies of the diversity of lactobacilli in the vaginal microbiota of reproductive-age women showed that prevalence of some lactobacilli varies in patients with different types of vaginal flora [11]. Perhaps, there is an association between the diversity of lactobacilli in patients with moderate dysbiosis and the presence of subjective symptoms and objective signs of vaginal inflammation.

    We cannot rule out the possibility that clinical manifestations of pathology in moderate dysbiosis depend on the diversity and abundance of opportunistic bacteria inhabiting the vagina.

    The aim of this study was to estimate the correlation between some microbiological characteristics and the presence of clinical signs of vaginal infection in patients with moderate vaginal dysbiosis. The study was carried out in women with moderate vaginal dysbiosis aged 18 to 53 mean age was Exclusion criteria were HIV, parenteral hepatitis, sexually transmitted infections, namely Treponema pallidum, Neisseria gonorrhoeae, Chlamydia trachomatis, Mycoplasma genitalium, and Trichomonas vaginalis, and antimicrobial therapy started as early as 4 weeks before the study.

    Samples posterolateral vaginal wall swabs were collected into Влагалища tubes containing 1 ml sodium chloride solution. Identification and quantification of 6 Lactobacillus species Lactobacillus crispatus, L. Patients were questioned about their complaints and examined to identify clinical signs of infection-induced inflammation of the lower genital tract.

    Statistical analysis was performed using Microsoft Office Excel Significance of differences was estimated by the two-tailed Fisher's test using WinPepi software. All patients gave their informed consent. All patients were divided into two groups depending on влагалища presence of clinical signs of an inflammatory infection II in the lower genital tract.

    Group 1 consisted of 91 patients with clinical signs of II, group 2 included 44 healthy women. We attempted to establish associations between the proportion of lactobacilli in the microbiota, the dominant species of lactobacilli, размер dominant species of opportunistic microorganisms OMsand II. Then the relative share of each subgroup in groups 1 and 2 влагалища estimated Fig.

    The difference between the groups was insignificant. Prevalence of dominant Lactobacillus species in groups 1 and 2 was different Fig. Prevalence of L. GPP in every second woman with or without clinical signs of II.

    Other OMs were far less common. No significant difference was revealed between OM prevalence in groups 1 and 2 see the Table. Study results demonstrate that lactobacilli inhabiting the vagina of reproductive-age women are represented mainly by L. It is noteworthy that L. A number of researchers have demonstrated that the presence of these lactobacilli is associated with an increased risk of bacterial vaginosis and poor pregnancy outcome [].

    Previously, we showed that L. Frequent detection of L. At the same time, moderate dysbiosis characterized by dominant L. Moreover, L. Recent studies show that L. Therefore, dominance of L. We were unable to identify an association between the proportion of lactobacilli in the microbiota and the presence of II in patients with moderate vaginal dysbiosis.

    However, the obtained results may have been influenced by a small patient sample size, which means that such an association remains a possibility. In more than half of patients with moderate vaginal dysbiosis, opportunistic bacteria were represented by GPP. In the studies in vitro Gardnerella vaginalis, a member of the GPP group, was shown to have влагалища high adhesion capacity [19, 20] and stimulate growth of other OMs, including Женщин bivia, also a GPP representative [19].

    It was hypothesized that G. This can explain high prevalence of GPP as dominant opportunistic pathogens размер patients with moderate dysbiosis. It is possible that as dysbiosis progresses, the contribution of other OMs to pathology increases; this may be true for Atopobium vaginae, a microorganism associated with vaginal dysbiosis []. In размер study A. However, the difference was not statistically significant. We assume that the lack of significance was due to the small number of healthy women in group 2.

    Dominance of Lactobacillus iners in the Lactobacillus community of the vaginal microbiota of women with moderate dysbiosis is associated with clinical signs of the infection of the lower genital tract, while dominance of L.

    Thus, these microorganisms can be used as microbiological markers when it is unclear whether dysbiosis requires treatment. Vaginal microbiome of reproductive-age women. DOI: Characterization of vaginal microbial communities in adult healthy women using cultivation-independent methods.

    Differences in the composition of vaginal microbial communities found in размер Caucasian and black women. ISME J. The vaginal bacterial communities of Japanese women resemble those of women in other racial groups. N Engl J Женщин. Handelsman J. Metagenomics: application of genomics to uncultured microorganisms. Microbiol Mol Biol Rev. Diversity of human vaginal bacterial communities and associations with clinically defined bacterial vaginosis.

    Appl Environ Microbiol. Prevalence and abundance of uncultivated Megasphaera-like bacteria in the human vaginal environment. Phenotypic and phylogenetic characterization размер a novel Lactobacillus species from human sources: description of Lactobacillus iners sp. Возрасте J Syst Bacteriol.

    Journal of Ural Medical Academic Science. Quantitative variations in влагалища vaginal bacterial population associated with asymptomatic infections: a real-time polymerase chain reaction study.

    Preliminary characterization of vaginal microbiota in healthy Chinese women using cultivation-independent methods. J Obstet Gynaecol Res. The identification of vaginal Lactobacillus species and the demographic and microbiologic characteristics of women colonized by these species. J Возрасте Dis. Characterisation of the vaginal Lactobacillus microbiota влагалища with preterm delivery.

    Sci Rep. Longitudinal analysis of the vaginal microflora in pregnancy suggests that L. BMC Microbiol. Comparative meta-RNA-seq of the vaginal microbiota and differential expression by Lactobacillus iners in health женщин dysbiosis.

    At the crossroads of возрасте health and disease, the genome sequence of Lactobacillus iners AB Int J Mol Sci. Analysis of adherence, biofilm formation and cytotoxicity suggests a greater virulence potential of Gardnerella vaginalis relative to other bacterial-vaginosis-associated anaerobes. Response of Gardnerella vaginalis biofilm to 5 days of moxifloxacin treatment. Adherent biofilms in bacterial vaginosis. Obstet Gynecol. The association of Atopobium vaginae and Женщин vaginalis with bacterial vaginosis and recurrence after возрасте metronidazole женщин.

    Association of Atopobium vaginae, a recently described metronidazole resistant anaerobe, with bacterial vaginosis. BMC Infect Dis. Molecular quantification of Gardnerella vaginalis and Atopobium vaginae loads to predict bacterial vaginosis.

    Clin Infect Dis. Rapid detection of Atopobium размер and association with organisms implicated возрасте bacterial vaginosis. Mol Cell Probes.