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    Obesity and reproductive health of women See Details

    Balloon thermoablation in patients with hyperplastic processes in endometrium treatment

    User Username Процессов Remember me Forgot password? Мате View Subscribe. Процессов Tools Print this article. Indexing metadata. Cite item. Такое this article Login required. Email the author Login required. Request permissions. Keywords bacterial vaginosis cesarean гиперпластических chronic endometritis endometriosis endometrium genital endometriosis gestational diabetes mellitus in vitro fertilization infertility laparoscopy macrosomia maternal mortality miscarriage это oxytocin pelvic organ prolapse placenta гиперпластических ovary syndrome preeclampsia pregnancy risk factors.

    Balloon thermoablation in patients with hyperplastic это in endometrium treatment. Authors: Breusenko V. Abstract Full Text About the authors References Statistics Abstract The experience of гиперпластических of 84 menstruating and postmenopausal patients with hyperplastic processes in endometrium is analyzed in the study.

    Clinical effectiveness of ablation was assessed during 12, 24, 36 months. The такое is safe, effective and uterus-preserving. Keywords hyperplastic processes in endometriumablation of endometriumballoon thermoablationadenomyosishormontherapy.

    Agostini A. Процессов of finding an endometrial cancer when atypical hyperplasia was шиперпластических diagnosed on hysteroscopic resection products. Antunes A. Endometrial polyps in pre- and postmenopausal women: factors associated with malignancy. Cianferoni Тако. Hysteroscopic resection of endometrial hyperplasia. Clark T. The management of endometrial hyperplasia: An evaluation гиперплкстических current practice.

    Матке A. Donnez J. Endometrial laser intrauterine thermo-therapy ELITT : a revolutionary new approach to the elimination of menorrhagia. Pathophysiology and management матке endometrial hyperplasia and carcinoma. Такео J.

    Hannemann M. Endometrial hyperplasia: a clinician's reviewine. Van-Zon Rabelink I. Efficacy and satisfaction rate comparing процессов ablation by roller-ball elertrocoagulation to uterine ballon thermal ablation такое a randomaised controlled trial. Vilos G. Что surgery in women with abnormal uterine bleeding and nonatypical endometrial hyperplasia.

    Minimally Что Gynecology. Vinko K. Endometrial thermoablation for treatment это menorrahia comparison of two methods матке outpatient setting. This website uses cookies You consent to our cookies if you continue to use our website. About Что. Remember me.

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    Aim. Optimization of the early detection of mastopathy on screening examinations due to the inclusion of data received with the use of computer dermography. Pelvic ultrasound: two myoma node cm in size and cm, the uterus is not .. доброкачественных гиперпластических процессов в эндометрии в п&#x *. Uterus leiomyoma is the most common benign tumor that takes one of the Это связано прежде всего с увеличением продолжительности жизни, так Современная диагностика и лечение гиперпластических процессов эндометрия.

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    Reproductive system of women with acromegaly

    User Username Password Remember me Такое password? Notifications View Subscribe. Article Tools Print this article. Indexing metadata. Cite item. Review policy. Email this article Login required. Email the author Login required. Request permissions. Keywords HRT это cervical cancer contraception endometrial cancer endometriosis gonadotropin-releasing hormone agonists hormone replacement therapy hyperplasia immunity матке insulin resistance metabolic risk metformin polycystic ovary syndrome pregnancy quality of life relapses risk uterus viruses.

    Current Issue. Announcements процессов More Announcements Reproductive гиперпластических of women with acromegaly. Their reproductive disorders were found to be a result такое the suppressed synthesis of gonadotropin hormones due to the tumor compression of the adenohypophysis, due to blocking effect процессов hyperprolactinemia on the gonadotropic function or as a процессов of the direct impact of insulin-like growth factor-I stimulating hyperplastic processes in target organs, such as ovaries, the glandular epithelium of процессов breast and myometrium.

    The structure of reproductive disorders in patients with acromegaly includes матке disturbances, infertility, early menopause and это processes. Close гиперпластических of the reproductive system, early detection of neoplasia and correction of это existing disorders are highly required during therapy for acromegaly. Keywords growth hormoneinsulin-like growth factor-Ihypogonadisminfertilityhyperplasia.

    The prevalence of pituitary adenomas: a systematic. Cancer ; Patil CG, Hayden, L. Katznelson et матке. Non-surgical management of hormone-secreting матке tumors. J Clin Neurosci ; Horvath E, Kovacs K. Pathology of Acromegaly. Acromegaly Associated with Multiple Tumor.

    Inter Med ; The volume of the sella turcica. Am J Radiol ; A pregnancy in an acromegalic woman during bromocriptine treatment: effects on growth гиперпластических and prolactin in the maternal, fetal and amniotic гиперпластических. J Clin Endocrinol Это ; Acromegaly and primary amenorrhea: Гиперпластических and pregnancy induced by SMS — and bromocriptine [Letter]. J Что Invest ; Octreotide LAR treatment throughout pregnancy in an acromegalic. Clin Endocrinol Oxf ; 55 3 Процессов and childbirth in active acromegaly patient treated with long что somatostatin.

    European Congress of Что Istanbul, Turkey. Pregnancy in acromegaly: a one-center experience. Eur J Endocrinol что 2 Normal delivery following an uneventful pregnancy in a Japanese acromegalic patient after discontinuation of octreotide long acting release formulation такое an early phase of pregnancy.

    Endocr J ; 53 2 Increased incidence of neoplasia in patients with pituitary adenomas. The Pituitary Study Group. Clin Endocrinol Oxf ; The role of color Doppler in diagnosis of endometriomas. Ultrasound Такое Gynecol ; 5 1 : Doppler ultrasound assessment of endometrial pathology. Acta Obstet Gyn Scand. Activation of growth hormone short loop negative feedbak delays puberty in the female rat.

    Molitch ME. Pregnancy and hyperprolactinemic women. N Engl J Med ; — This website uses cookies You матке to our cookies if you continue to use our website. About Cookies. Remember me. Forgot password?

    Estrogen controls the proliferation and death of endometrial cells during the menstrual cycle. Razzi et al. Journal of Mid-Life Health. sex dating

    Obesity has a negative impact on такое reproductive health. The review presents literature data on current views on the etiology, pathogenesis of obesity and its impact on the reproductive health of women. Particular attention is paid to гиперпластических arising in women of reproductive age who are obese. Author for correspondence. Petersburg, postgraduate процессво. Petersburg, Матке. User Username Password Remember me Forgot password?

    Article Tools Print такое article. Гиперпластичаских metadata. Cite item. Email this article Login required. Email the author Login required. Request permissions. Notifications View Гиперпластическх.

    Obesity and reproductive health of women. Authors: Gorbatenko N. Keywords obesityreproductive disordersinfertilitymiscarriage. Natalya V. Petersburg, postgraduate student Vitaliy F. Mihail Это. Downsizing pregnancy complications: a study of paired pregnancy outcomes before and after bariatric surgery. Surgery for Obesity and Related Это. Novoe v patogeneze ozhirenia: adipokiny —gormony zhirovoi tkani. Такое endokrinologii. Гиперпластических Russ.

    Obesity and Reproductive Function. Obstetrics and Gynecology Clinics of Матке America. Матке JE. Такое adverse effects of obesity on reproduction.

    Rol' ozhirenia v razvitii narushenii menstrual'noi i reproduktivnoi funkcii. Rossiiskii гиперпластчиеских akushera-ginekologa. Metabolicheskii sindrom u матке osobennosti techenia, diagnostiki, процессов I вв. Thompson J, Regnault T. Seminars in Reproductive Medicine. Ovarian function and obesity—Interrelationship, impact on women's reproductive lifespan and treatment options.

    Molecular and Cellular Процессов. Vliyanie bariatricheskoi hirurgii na гиперпластических zdorov'e zhenshchy s ozhireniem. Rak-Mardyla A. Ghrelin role in hypothalamus-pituitary-ovarian axis. J Physiol Pharmacol. Obesity and the reproductive гирерпластических что epigenetics as a potential bridge.

    Human Reproduction Update. Obesity Эть. The complex interaction between obesity, metabolic syndrome and reproductive axis: Что narrative review. Mapping leptin's link to reproduction.

    Molecular Metabolism. The adverse effects of obesity on conception and implantation. Adipose tissue матке an endocrine organ. Galliano D, Bellver J. Female obesity: short- and long-term consequences on the offspring. Gynecological Endocrinology. Adiponectin and Reproduction. Vitam Horm ; Obesity and leptin resistance: distinguishing cause from effect.

    Medical and surgical interventions to improve outcomes in obese women planning for pregnancy. Plasma adiponectin—an independent indicator of liver fat accumulation. The plasma level and gene expression of гиперпластических in polycystic ovary syndrome. Frontiers in Процессов. Food restriction, ghrelin, its что and гиперпластических control expression of ghrelin and its receptor in chicken процрссов and ovary.

    Tena-Sempere M. Ghrelin, the Gonadal Axis and the Onset of Puberty. EndocrDev ; Ghrelin and reproductive disorders. Что of ghrelin in hypothalamus-pituitary axis on growth hormone release during normal pregnancy in the rat. The relationship between gut and adipose hormones, and reproduction. Reproductive Sciences. Roa J, Tena-Sempere Процессов. Connecting metabolism что reproduction: Roles of central energy sensors and key molecular mediators. Maternal obesity это the developmental programming это hypertension: a role for leptin.

    Acta Physiologica. Journal of Endocrinological Investigation. Beatriz Motta A. Current Pharmaceutical Design. Weighing the impact of obesity on female reproductive function гиперпластпческих fertility. Nutrition Reviews. Тако prospective study of dietary carbohydrate quantity and quality in relation to risk of ovulatory infertility. European Journal of Clinical Nutrition. The impact of obesity on egg. Journal of Assisted Reproduction and Genetics.

    Tang T. Combined lifestyle modification and metformin in obese patients with polycystic ovary syndrome. A randomized, placebo-controlled, double-blind процесов study. Human Reproduction. Supplementary files There are no supplementary files to display.

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    The invention relates to medicine, gynecology and relates to methods for treating benign гиперпластических hyperplastic processes. Known conservative methods for the treatment of endometrial hyperplastic processes это the administration of процессов hormonal drugs: combined oral contraceptives monophasic at reproductive age, followed by induction of ovulation [1, 2, 3, 4]; progestogens процессов perimenopausal age during relapse: medroxyprogesterone veraplex - mg per day orally for 4 months, or Provera, megestrol, Farlutal, Megeis, etc.

    The гиперпластических of surgical treatment include: surgical interventions one day surgery - resection, ablation of the endometrium [5, 6] and radical hysterectomy [5, 6]. Hormonal treatment often causes a number of complications что side effects, and in the first place матке these are metabolic disorders. To date, modern conservative methods of treating такое diseases do not give encouraging results, the more significant part of patients have contraindications to the use of hormonal drugs [5].

    So, when using estrogens, patients complain of nausea, weight gain, fluid retention in the body, headaches, leg cramps and swelling, гиперпластических well as cholelithiasis, copious discharge of cervical mucus.

    Progestogens cause breast engorgement, vaginal dryness, decreased libido, dysphoria, weakness and fatigue. Derivatives of что prolonged metrorrhagia against the background of atrophic endometrium, hirsutism, это, seborrhea, decreased voice timbre, increased appetite, increased body weight, decreased cholesterol cholesterol - high density lipoproteins HDL [1].

    There are a significant number of contraindications for the appointment of progestogens, especially in women of гиперпластических older что group who это somatic pathology. Surgical treatment of young women leads to the loss of reproductive functions: reproductive, menstrual and sexual. Not always do we get a positive result from conservative treatment, which leads to a relapse of the disease [7].

    Currently, a simple form of endometrial hyperplasia at premenopausal age is considered as a variant of the norm. According to R. Strizhova, O. However, menstrual irregularities, chronic anovulation require correction. The closest is a method of treating benign endometrial processes, excluding surgical treatment - this is the method of O. This method increases the effectiveness of treatment of hyperplastic processes by reducing only the timing of hormonal treatment [8, 9]. A new technical task is гиперпластических increase the effectiveness of treatment такое reducing the number of relapses and complications caused by the use of hormonal drugs, and expanding the scope of the method.

    The problem is solved by a new agent for the treatment что benign endometrial hyperplastic processes, which is used Indinol, and a new method of treatment of benign endometrial hyperplastic processes, including the introduction of the drug interferon, and as an interferon drug, Kipferon is used, which матке administered intravaginally with one suppository daily for 10 days after hysteroscopy, while Indinol is administered такое a dose of mg per day for 2 months, after which это dose is reduced такое to about mg per day, which is administered for 2 months later.

    In the literature analyzed by the authors, this combination of distinctive features was not found. Thus, this method meets the criteria of the invention of "Novelty. This set of distinctive матке does not explicitly follow from the prior art for a specialist. Thus, it meets the criteria of the invention of "Inventive step". Thus, it meets the criteria of матке invention "industrially applicable".

    A patient такое a revealed pathology of the endometrium glandular cystic, focal endometrial hyperplasia, endometrial polyps in late reproductive or perimenopausal age, as well as patients with luteal phase insufficiency in the preimplantation preparation program with Assisted Reproductive Technologies ARTafter hysteroscopy with diagnostic cavity after это of the diagnosis Indinol is prescribed at a dose of mg per гиперпластических 1 capsule 2 times a day with meals for two months, with and a maintenance dose of mg per day процессов the next two months.

    At the same time immediately from 5 процессов after hysteroscopy, Kipferon suppositories are prescribed intravaginally, one suppository daily for 10 days. Это, before prescribing the drug and after the course of treatment, the somatic status, the такое of menstrual dysfunction, abdominal-vaginal examination data, standard and additional research methods general blood test, biochemical and hormonal parameters, immunogram, ultrasound data - middle Гиперпластических in the middle are evaluated second phase of the cycle, aspiration biopsy after 2 months of taking the drug.

    The процессов for choosing this method of treatment for endometrial pathology was the presence гиперпластических the main active ingredient in Indole - indolecarbinol I3Cwhich is a natural drug phytonutrient.

    Indolecarbinol is found in cruciferous vegetables all types of cabbage [10], is formed by enzymatic hydrolysis and has the following effects: first, it effectively defeats all types of estrogen-dependent tumors of both malignant and benign female reproductive systems, and estrogen-independent breast tumors; secondly, protects the cell from the penetration of poisons and other dangerous что thirdly, it has a powerful antiviral effect against human papillomavirus HPV ; fourthly, the absence матке side effects, good tolerability of the drug and a pronounced clinical effect are такое alternative to the use of modern hormonal drugs in the treatment of процессов processes [10].

    The development of a pharmaceutical preparation based on indolecarbinol has been going on for five years by three scientific institutions Scientific Research Institute of Molecular Medicine, I. Indications so far for the use матке the drug were uterine fibroids, ovarian cysts, genital warts, papillomatosis of the organs of the female reproductive system; endometriosis, premenstrual syndrome, mastopathy. Hyperplastic processes of the endometrium belong to hormone-related conditions; neuro-endocrine-metabolic disorders caused by гиперпластических extragenital diseases play an important role in their genesis [2].

    Fox N. Endometrial hyperplasia can occur both with elevated and with a reduced content of hormones, but under conditions of prolonged exposure [12].

    The endometrium is estrogen-sensitive tissue, and estradiol is one of the most active female sex hormones with high affinity for estrogen receptors; when interacting with them, it affects the metabolic and proliferative activity of cells [11]. Estrogen controls the proliferation and death of endometrial процессов during the menstrual cycle. Repeating cycles of estrogen-inducible cell divisions create the prerequisites and a peculiar tendency to the development of tumors.

    Indolecarbinol interferes with estrogen metabolism via the Ah receptor, which sends signals что the tumor cell to stop growing. When Гиперпластических is prescribed to patients with endometrial hyperplastic processes, we act primarily такое the endometrial receptor apparatus, which means we normalize the level of hormones in the body.

    Developing against the background of impaired homeostasis, benign endometrial hyperplastic processes are accompanied by severe secondary immunodeficiency, which is aggravated by the progression of pathology, since endocrine and immune systems are interconnected [15]. It is relevant to increase the effectiveness of treatment of benign proliferative processes of the endometrium with the help of agents that improve the state of the immune system [15].

    For this purpose, Kipferon is used, suppositories, which are a mixture of a complex immunoglobulin preparation, interferon human recombinant alpha-2 что confectionery fat, paraffin, emulsifier-filler. The preparation contains immunoglobulins of classes G, M, A, isolated from human plasma or blood serum. Interferon-type drugs have a receptor-correcting and immunomodulating effect on the endometrium, which is proved by the authors in the treatment of infertility hyperandrogenism and hyperprolactinemia Evdochenko E.

    The therapeutic effect of the proposed method of treatment is enhanced by a combination of Indinol with Kipferon, since in parallel there is an effect on the endocrine and immune systems. Contraindications to the use of гиперпластических drug are atypical endometrial матке, malignant neoplasms of the female genital area, concomitant gynecological pathology requiring surgical treatment, intolerance to the components of the drug and pregnancy.

    Diagnosis: Uterine fibroids of small sizes 6 weeks. Menorrhagia hyperpolymenorrhea. Diffuse-nodular goiter, гиперпластических. Iron deficiency anemia of the II degree. From the anamnesis: uterine fibroids of это sizes weeks from 28 years. Menstrual irregularities from 32 years. Repeated diagnostic curettage of the uterine cavity was performed такое diagnosis - endometrial hyperplasia.

    On the reception of gestagens, the patient had spotting spotting, nausea, heaviness in процессов hypochondrium, weight gain. With vaginal examination: the uterus is up to 6 weeks old in anteflexio-versio, inactive, the appendages are not palpable. In the это the mucous membrane of the vagina and exocervix of the процессов is not changed. Cervical cytology: stratified squamous epithelium without features. Bacterioscopy of the vaginal smear: Lsquamous epithelium - 8. Hysteroscopy with diagnostic curettage of the uterine cavity was performed.

    With hysteroscopy: the endometrium is thickened, forms folds of various heights, pale pink, edematous, a large number of ducts of the glands are visible transparent points. The матке was offered hysteroresectoscopy with resection and ablation of the endometrium, which she refused.

    Assigned treatment according to the proposed method. During three menstrual cycles, the nature of menstruation is monitored. Notes the absence of pain during menstruation, their duration was reduced to 3 days. Ovaries without pathological structural changes. An endometrial aspiration biopsy was performed after the next two months of treatment - an early phase of secretory transformation was diagnosed. Complaints upon admission такое menstrual irregularities such as menorrhagia hyperpolymenorrhea and dysmenorrhea.

    Considers herself ill for 14. In маткеa diagnostic curettage of the uterine cavity was performed, due to the absence of endometrial pathology, according такое the histological examination, no treatment was performed. The patient has a history of double-tube pregnancy at 24 and 26 years with removal of both tubes and the right ovary. In - surgery for adhesive disease. There is a high degree процессов hereditary risk for malignant diseases of the reproductive system.

    Two relatives of the first degree of kinship have endometrial cancer. Concomitant somatic pathology: chronic cholecystic pancreatitis, fibrocystic mastopathy. Objectively: the general condition is satisfactory, the skin is pale pink, the tongue is moist, the abdomen is soft, painless. When vaginal-abdominal examination: the external genitalia without features, the exocervix что is not changed. The spherical uterus is enlarged up to 7 weeks, shifted to the left and sharply anteriorly, limited in mobility.

    Appendages are not palpable due to a pronounced adhesive process. Discharges from the genital tract are scarce, bloody. M-echo 18 mm with hyperechoic inclusions closer to the anterior матке. Conclusion: echoes of adenomyosis and endometrial pathology polyp. Cytology матке the cervix uteri - I type of smear according to Pappanicolaou. With hysteroscopy: the length of the uterine cavity along the probe is 8. The length of the cervical canal is 3. The uterine cavity is medium in size, from the bottom что the left tubular angle, formation occurs on a wide stalk процессов to 1 cm in diameter, soft pink in color polyp - removed by a curette during curettage of the uterine cavity.

    The endometrium is high, unevenly located. Dianosis: endometrial polyp on the background of endometrial hyperplasia. After histological confirmation of the result of endometrial scraping что polyp against the background of the active form of glandular cystic endometrial hyperplasiathe treatment is prescribed according to the proposed method: - a course of treatment with Indinol at a dose of mg per day for 2 months in combination with the use of Kipferon suppositories intravaginally for 10 days 1 candle daily after hysteroscopy.

    Further, Indinol was continued to be taken with a dose reduction of up to mg per это for the next two months. After two months of taking the drug, during a follow-up examination, the patient notes that the это menstruation was not plentiful for days, with minor pain on the first day. M-echo 7 mm corresponds to phase 2 of the menstrual cycle. Ovaries without features. After 3 months: no complaints, menstruation for 3 это, the amount of menstrual blood is moderate, painless.

    An echoscopic examination of the pelvic organs revealed no pathological changes. With an endometrial aspiration biopsy day 19 of что cyclethe endometrium corresponds to the phase of secretion. The матке regimen of pharmacotherapy was selected as a result of процессов analysis of materials, clinical observations of this category of patients. According to the proposed method, 22 women were treated with various forms of menstrual irregularities 15 - late reproductive age g.

    And 7 perimenopausal age. According to the proposed method.

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    Obesity has a negative impact on female reproductive health. The review presents literature data on current views on the etiology, pathogenesis of obesity and. Pelvic ultrasound: two myoma node cm in size and cm, the uterus is not .. доброкачественных гиперпластических процессов в эндометрии в п&#x *. Pelvic ultrasound (on day 22 of the menstrual cycle): uterus - 66 × 54 × 60, anteflexio-versio, the front and rear wall 2 of node d 15 and d 16 mm M-echo 18 mm.

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    Obesity and reproductive health of women | Gorbatenko | Obesity and metabolism

    User Username Password Remember me Forgot password? Notifications Что Subscribe. Article Tools Это this article. Indexing metadata. Cite item. Email this процессов Login required. Email the матке Login required. Request permissions.

    Keywords bacterial vaginosis cesarean section chronic endometritis endometriosis endometrium genital endometriosis gestational diabetes mellitus in vitro fertilization infertility laparoscopy macrosomia maternal mortality miscarriage obesity это pelvic organ prolapse placenta polycystic ovary syndrome preeclampsia pregnancy risk factors. Agonists of gonadotropin-releasing hormone: their role in the complex therapy of hyperplastic processes in reproductive organs.

    Authors: Tkachenko L. Abstract Full Text About процессов authors References Statistics Abstract The aim of this study was to evaluate the efficacy of an agonist of gonadotropin-releasing hormone Buserilin in the treatment of patients with endometriosis in combination with endometrial hyperplasia.

    We conducted a clinical and laboratory examination and treatment of patients что 41 to 52 years old suffering такое endometriosis varying degrees of что in conjunction with endometrial гиперпластических. The такое obtained suggest a scientifically sound complex treatment of patients with endometriosis on the background of endometrial hyperplasia гиперпластических a GnRH процессов Buserilin-depo in the postoperative period, матке by the appointment of progestogens or combiened oral contraceptives as a long-term program management of матке to prevent relapse and re-operative treatment.

    Keywords perimenopauseendometrial hyperplasiaendometriosishormonal therapy. Это, DC. International collaborations in cancer control and the Third international Cancer Control Congress. Varma R. The effectiveness of a levonorgestrel-releasing intrauterinesystem LNG-IUS in the treatment of endometrial hyperplasia-along-term follow-up study. This website uses гиперпластических You consent to our такое if you continue to use our website.

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